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Avengers

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Posts posted by Avengers

  1. On 8/17/2021 at 7:38 PM, BootmanLA said:

    Second, if I'm not mistaken, the strain might be PrEP resistant, but once the guy's on treatment (thus introducing the other medications needed to combat HIV), it should bring his viral load down low enough that he can't infect anyone else, whether or not they're on PrEP. And not all HAART regimens use the same chemicals as in Truvada and its generic equivalents, so while the strain may be resistant to that particular pair of drugs, it may not be resistant to other drugs in the same class (much less the third and/or fourth kinds of drugs in most HAART medications).

    Very good information. Multidrug resistant strains do exist and that would be a nightmare. We must take our medications regularly and should not fetishize about mixing and matching strains (but this concept of mixing and matching isn't well understood by the scientists).

    The good news is it is extremely unlikely that someones genotype test will say that the patient's HIV is resistant against all drug classes. Even if that unlikely case happens, there's still hope. A new drug Lenacapavir brought down the viral load in 88% of heavily treatment experienced patients with multidrug resistant HIV in a recent clinical trial. It is so wonderful to live now compared with 1985.

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