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CRISPR/Cas9 and HIV... a possible definitive solution???


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Hi!!, 

CRISPR/Cas9 is a novel DNA editing technique, that worth the nobel prize in chemistry 2020...

From Wikipedia: 

"CRISPR  is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti-phage) defense system of prokaryotes and provide a form of acquired immunity. CRISPR are found in approximately 50% of sequenced bacterial genomes and nearly 90% of sequenced archaea.

Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and cleave specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within organisms. This editing process has a wide variety of applications including basic biological research, development of biotechnological products, and treatment of diseases. The development of the CRISPR-Cas9 genome editing technique was recognized by the Nobel Prize in Chemistry in 2020 which was awarded to Emmanuelle Charpentier and Jennifer Doudna."

What is interesting about HIV; some NATURE articles: 


[think before following links] https://www.nature.com/articles/s41467-020-19821-7

[think before following links] https://www.nature.com/articles/s41596-018-0069-7

[think before following links] https://www.nature.com/articles/d41586-019-02076-8

 

What are your thoughts???

 

Greetings!!

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