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Have been on Descovy for 18 months or so and have gained 15 to 20 pounds.  I called the clinic and was told that unwanted weight gain can be a side effect for some people on Descovy.  I don't know other men on Descovy so I figured I'd reach out here.  Have other men experienced weight gain on Descovy?

Posted

I was on Truvada for about 5 weeks when I first tried it and had a number of side effects, one of them was weight gain. I gained 11 pounds in those 5 weeks even though I was felt nauseous for about 5 hours after taking the pill.  Because of the side effects, my doctor switched me to Descovy. I gained 4 pounds in the 2 weeks I was on Descovy. I stopped taking PrEP and within a month the weight all came off. I didn't changed anything else--not my exercise routine, diet, supplements nor anything else. I think weight gain is one of the side effects of those medications.   

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