6811283

You "sometimes hear that people have turned while on PrEP" because the tiny number of cases (2 or 3) have been blown way the fuck out of proportion by anti-PrEP fanatics. The stuff works, really well, if you take it every day. Better than condoms. (You don't see headlines every time someone gets HIV while using a condom -- and that happens every fucking day).

Take the pill religiously and go to your doctor every three months as required, and rest assured that you're more likely to win the PowerBall than to get HIV.

However, if you start having more raw sex than before, the tradeoff will be a higher risk of STDs. Get tested often (quarterly is best). And be honest with your wife about that risk. You are protected against HIV, and the others are curable (or, in the case of herpes, also blown way out of proportion by scaremongers).

Three more tips: (1) Have a good long gargle with antiseptic mouthwash (like Listerine), deep in your throat, after sucking cock. You can get STDs down there and this helps kill them. (2) Try to piss after fucking raw. Helps clean bacteria out of your dick. (No guarantees, it's folk wisdom, but it seems to work for me). (3) DON'T douche after getting fucked. Contrary to what some people think, it doesn't prevent infections -- it can irritate your rectal tissue and make infections MORE likely. If you want to douche BEFORE getting fucked, do so early, and give your hole a couple of hours to recover from irritation.

On 6/3/2017 at 5:55 PM, connorca said:

Hi everyone, 

I'm Connor. I'm kinda new to everything here... but not new to everything gay. I had my first experience sucking cock/swallowing cum at 10 and just let it go from there. I've been 100% into condoms until just recently when I stumbled onto some poz porn or breeding porn, I guess, and it really got me interested in everything here. 

Welcome! You will read a lot of wild stuff on here. Don't feel like you need to emulate it any time soon. Your health is important and you have your whole life ahead of you.

7 minutes ago, rawfuckr said:

There's lots of bug-chasing dreamers around here who don't view PrEP very positively because diminishes the fun. All these anti-PrEP comments here need to viewed in that context... 

I get why some guys aren't happy with how PrEP is reducing the pool of virus out there. I decided to quit PrEP myself for my personal reasons and I'm happier.

But not everyone wants the bug. People have the right to make their decisions based on scientific fact, not rumor. I have lots of non-chaser friends who are on PrEP and it's been a godsend for them to be able to enjoy bb like the rest of us.

They're more likely to get struck by lightning than to get pozzed. But every time another overblown rumor goes around about PrEP failing, they freak out and it ruins sex for them again.

On 12/18/2016 at 6:48 AM, lj1987 said:

I have been invited to a chem-sex breeding party with five other guys. All poz and Not meditated. Should I go? I am on prep but I want to know what are the risks in terms of hiv that I need to be aware of?

How about an update, lj1987? Did you end up going? How was it? Catch any minor buggies?

On 5/22/2017 at 9:13 PM, timfreo said:

Many more cases to come. Resistance to PREP is rising

Do you have any actual data to back that up, or is that just anti-PrEP wishful thinking? Truvada-resistant strains are extremely rare. None of the researchers has raised any alarm about them becoming more common. 

No further word from cuntboi... his last login was just a few months after he posted about his decision to let it all go. I have to imagine he finally did completely self-destruct and his life was snuffed out, either actively or passively. I hope he enjoyed himself along the way but I can't help but be sad about all the wasted years that he might have enjoyed on the future. You can be a total cumslut and keep the ride going for years -- in a spirit of joyful abandon rather than self-destruction. Seems a shame to burn out so quickly.

The guy sought out PrEP because he knew he was at risk and didn't feel he could change his behavior. He was being responsible under the circumstances.

The "shame, shame, shouldn't have done all that sex and all those drugs" attitude from some posters here -- members of a group that is devoted to highly stigmatized sexual behavior -- is really hard to fathom.

18 hours ago, Upstateguy518 said:

It was because this guy was treating his body like a fucking outhouse and filling it with whatever cock and drug he could get his hands on.

It may be the case that this guy pushed the boundaries of what PrEP can protect against, and that most other people are not at risk of the same. But I would be careful about characterizing anyone else's sexual behavior in terms like "treating his body like a fucking outhouse." Most of us have what the straight world would consider pretty out-there sex lives. Judge not, lest ye be judged.

I've tried starting a couple of new posts (under Backroom/Testimonials). This always worked before, but now the posts are showing up shaded in pink with a little warning triangle icon. What's wrong? Thanks.

9 hours ago, MuscledHorse said:

I work in the direct patient care, non-administrative side of health care. I have a doctorate in pharmacy as well as other degrees, so you can bet i know my medicinal and organic chemistry as well as my pharmacology, microbiology and immunology. 

OK, thanks for clarifying.

6 hours ago, nbcb21 said:

Theoretically, this has always been possible [snip] This is the 1% they're talking about when they say up to 99%.  Also, forgive any mistakes, while I do work in science, it's been some time since I've had anything to do with virology/HIV specifically.

Thanks for the fascinating, succinct explainer. Of course it sucks that this guy got infected, but what an interesting case.

2 hours ago, Sarif98 said:

I work in healthcare as well and completely agree with you there. 

Approximately 1 in 8 Americans "work in healthcare" -- a term that can mean anything from receptionist to brain surgeon. Unless you are an HIV scientist qualified to pronounce on the validity of this research, the fact that you "work in healthcare" really isn't relevant.

27 minutes ago, Bluepanther89 said:

Yikes! I did not even consider the localized gut infection factor; makes one wonder if slight bleeding while bottoming even on Prep reduces protection.

I don't think that's what this is about. You can bet that of the 199,997 people on PrEP who did NOT seroconvert, some of them had slight (or not-so-slight) bleeding -- and they were still fine.

You can drive yourself nuts reading these extreme outlier cases and spinning all kinds of scary fantasies. You might as well obsessively read about every freak car accident and worry yourself sick every time you get in a car. Could you, theoretically, get HIV while taking PrEP correctly? Yes -- but the odds are so extremely low that it simply doesn't make sense to worry about it.

2 hours ago, Bluepanther89 said:

From what i have read and researched Prep Truvada only protects you up to 70% if you are im not sure intravenous or recreational drug user; so if he was indeed doing every drug out there it all makes sense now; his protection levels were reduced 29%!

Recreational drugs can only transmit if used intravenously -- not from snorting, smoking, etc. The patient reported injecting ketamine twice, with clean needles. The researchers seem to believe him (he appears to have been scrupulously honest otherwise), and the assumption is that the transmission was indeed sexual. An intravenous infection wouldn't have resulted in the localized HIV infection in the gut that is the hypothesis. There are still many mysteries about this case, but I'm sure the researchers are well aware of the possibility of IV infection, and have ruled it out with good reason.

See: http://www.aidsmap.com/page/3118230/

20 minutes ago, DylanM1999 said:

Keep in PrEP was supposed to be used with a condom as well. Not just taking prep and going BB

And condoms are "supposed to" be used with oral sex -- it's in the CDC safer sex guidelines. These messages are always crafted to be as risk-averse as possible (often for legal liability reasons). It's just like the warnings on the package that you could die from taking Tylenol. The manufacturer of Truvada had to agree to include the condom warning in order to get FDA approval (largely because public health authorities want to keep scaring people into using condoms, to prevent other STDs).

The study results are clear: PrEP prevents HIV infection in well over 99% of cases, whether or not you use a condom. The subjects recruited for the trials were all chosen because they were at very high risk -- most were already not using condoms. They didn't suddenly start using them once they got on PrEP -- but they stopped seroconverting. 

You can choose to use condoms if you want, to reduce the risk of other STDs. But to say that everyone needs to wear them because 3 people got HIV out of approximately 200,000 PrEP users is absurdly overcautious.

14 minutes ago, rawfuckr said:

Still the way he turned + is very strange. Got + AB test with negative/UD PCR test, even with very fine lab HIV testing. If he was taking truvada consistently, and from his dry blood spot samples seems he was, how was he able to seroconvert without a significant viral load? No one knows and its a mistery.

It's pretty fascinating -- this thing about a localized infection in his gut, never heard of such a thing. This case could potentially reveal a good bit about how HIV works. There are mysteries and outliers in every area of medicine... for example, spontaneous remission of Stage 4 cancer.

We'll never understand everything, but we know enough about PrEP at this point to be confident that it is at least as effective as most vaccines or other preventive interventions. It's still a resounding success, even though the naysayers are going to grab every negative story to try to discredit it (something they never do with the tens of thousands of infections due to condom failure).

On Thu Feb 23 2017 at 2:52 PM, shyvers said:

And the frequency is shortening. It feels that the PReP BB spring is coming to an end. Winter is coming and we may need to get back to wearing our hoodies.

The frequency is only shortening because the number of PrEP users is growing so rapidly. There are now probably upward of 200,000 people on PrEP. Three seroconversions = 0.0015%. Since the estimated effectiveness was always 99% max, that's way better performance than anyone expected. This isn't "winter," it's the small margin of error that's to be expected of a highly successful intervention that is -- like everything in life -- not 100%.

I choose not to take PrEP, for reasons others here have shared, but I fully support those who do, and I'm tired of the constant gloom and doom about its effectiveness. 

In the PrEP research trials, no one whose blood levels proved they had taken four or more doses a week contracted HIV. That is not to say that you should unilaterally drop your dosage below the recommended daily use -- just that there is evidence that protection is pretty good with a minimum of four doses. 

Estimated effectiveness breaks out like this:

2 times per week would result in a 76% risk reduction;
4 times per week would result in a 96% risk reduction; 
7 times per week would result in a 99% risk reduction.

For more info, see: https://www.facebook.com/PrEPFactsFAQ/posts/750294228421107

Do not assume that symptoms you are experiencing are due to Truvada just because they're happening now. Correlation does not equal causation -- things can be coincidences. Nor is there any guarantee that taking just 4 doses a week would reduce side effects.

It sounds like the safer course is to keep taking the meds as prescribed, continue to monitor your kidney situation, and listen to what your doctors say to you.

As for GI side effects like loose stools: more than likely these will continue to diminish with time. 

Prep made me lost almost 8kg.

Why don't you stop for a month or two?

Prep take more than a week to flush put of your system. It takes about a month.

Just be very aware of your risk factors if you stop taking PrEP. It's hard to revert back to using condoms if you quit them when starting PrEP. I know a guy (yeah, I know, anecdotes...) who stopped PrEP due to side effects and got HIV.

But assuming he's poz and has a high viral load, then even without PrEP, your chances of infection are considerably less than 1.4% which is the rate for having someone with a high VL cum in your ass. 

I think actually 1.4% is the *average* risk bottoming for an HIV+ top without protection, not for high VL specifically. In case of acute HIV infection (from a recent, untreated infection) the CDC calculates that risk is increased by a factor of 7.25. See: https://wwwn.cdc.gov/hivrisk/about_the_data.html

My experience -- your mileage may vary:

In 2 years on PrEP I've had gonorrhea twice and syphilis once. They weren't fun, but easily treated.

I feel better playing mostly with other guys on PrEP or poz guys under regular medical care -- since they're more likely to be tested every 3-6 months. But I'll admit sometimes it's hard to stay out of the sling at CumUnion and let a rando pump one into me.

I'd be more concerned if sexually transmitted Hepatitis C starts to become more widespread. So far that's pretty rare but I'm keeping an eye on the news coverage.

People have succeeded in getting PrEP covered as a military spouse. Check out the PrEP Facts Facebook page, which has 14,000 members. (It's a closed Facebook group -- your other Facebook friends won't see your activity). www.facebook.com/groups/PrEPFacts/

The risk to bottoms is indeed significantly higher than to tops.

Bottoming for an HIV+ top without condoms or PrEP carries about 1.4% chance of infection per fuck. On PrEP, this is reduced to 0.06%.

For tops, the figures are 0.1% unprotected, 0.004 on PrEP. Not technically zero, but might as well be.

See: https://wwwn.cdc.gov/hivrisk/estimator.html

Very few people experience side effects for more than a few weeks. Anything beyond that, you should definitely discuss with your doctor.

A good place to compare notes with other PrEP users about their experiences is the PrEP Facts Facebook group, with 14,000 members. (It's a closed group -- your other Facebook friends won't see your activity). www.facebook.com/groups/PrEPFacts

I keep reading guys here saying "I wish I could get PrEP but it's not available where I live." But people all over the world are getting PrEP using generics -- which are safe, inexpensive and good quality.

You can talk to PrEP users and find out more about how they've done it, by joining the Facebook group: https://www.facebook.com/groups/PrEPFacts/

(It's a closed group -- your activity does not show on your timeline and your other Facebook friends can't see it).