Leathercouple
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I guess this could be my situation so… best to take the 3 weeks of doxy.
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Thanks for the reply. I appreciate it what I’m concerned about is the clinic didn’t do a swab. It was based on an independent swab test I did myself some days before and the lab contacted me and said to go to my nearest GUM clinic. That clinic who prescribed the 3 weeks of meds didn’t do a further swab or blood tests. Just asked if I had symptoms of which I said I had what I called a sensation/wetness. No discharge etc. So no typing on the swab was done and no further swab taken. Would you know if it was LGV in your ass? As in more symptoms?
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Caught Chlamydia infection in my ass. Slightly symptomatic… red hole and “wet” feeling. Came back positive via rectal swab test in clinic. They prescribed 7 days of doxycycline 100mg 2x per day. All good… Then a few hrs later I get call from the testing clinic to increase the treatment duration to 3 weeks!! I’ve checked medical resources and published data and all day 7days is 99% effective for doxy. Certainly for azithromycin (1g in a single dose) the efficacy is not as good…in low 80%. But for doxy… seems much better even when on the 7 days. They didn’t have time to “type/profile” for a resistant strain and nothing suggests it is… any ideas why they want me to take for 3 weeks? I don’t wanot to take that amount of antibiotics due to impact on digestive system microflora. Thoughts? Experience?
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NBN/SBN have a new venue -open tonight
Leathercouple replied to Littlebill77's topic in London Metro Area
Is it low lights in the sauna or actually just like going to a sauna club ?(I can’t stand the latter). -
Leatherireland
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PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
Totally agree with all that has been posted. This is my personal experience with PreP. I’m one of the rare few where it impacted my liver function and caused severe fatty liver. The challenge now is that there is only 1 approved PreP med in my country - Truvada/genetic Truvada. All I would say to people going on PreP for the 1st time, is to have a baseline liver assessment (ALT,ALK etc) that then get checked 3 or 6 or 9 months into use. My experience is that in general healthcare zones in on kidney and bone markers for impact when on PreP, but there are other factors that warrant checking too. -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
New test results show 2/3rds fatty liver but no other damage. Looked back at blood work prior to Prep and since and there is a correlation to when I started on the Prep. Disappointed now as my bb days are over as this PreP won’t be good for me. Hopefully something new comes down the line soon. Thanks to all for the info and advices. -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
It definitely seems to be an issue with these meds and not necessarily joined the dots thinking by clinicians. I will have to stop PreP now as it’s impacting my liver a lot. -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
Problem is then I can’t take PreP so no raw fucking for me. -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
Thank you for this detailed response. I totally agree with your assessment. I am a slim guy but suffered for high cholesterol for years. Not diabetic or obese etc Ive asked my doctor for blood test results to period before I started on prep. I want to see if any signals there before prep. I’ve started a low fat/low sugar diet. Will see if that helps. I appreciate the response and info. Thank you. -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
It sounds like it! I’m wondering if it’s not the PreP doing this to my liver.... doesn’t seem like this happens a lot. -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
I sort of expected lots of input/discussion/experiences on this topic. A week later... why so quiet? -
PreP and Liver Disease (Fatty Liver or NASH)
Leathercouple replied to Leathercouple's topic in PrEP Discussion
Any info/experience out there on this ? -
Never posted before but like the discussions and dialogue on this site. I started PreP approx 2 yrs ago but I don’t take it regularly I.e. I dose up for vacations and weeks like Folsom etc, taking the meds for 7 days before events/sex, during (could be a few weeks of off and on sex, and then 7 days post last raw encounter. I am 100% top. Blood work done every 4-6 months. Sometimes more frequently. Each time there was slight elevated liver enzymes. Nothing was made of them as kidney and bone markers were fine. Just told it was from having a few beers over weekend. Though I drink not so much. Ever before starting PreP I had unknown cause IBS. Attending a gastroenterologist and had a recent liver and gall bladder ultrasound as part of the IBS checks. out of the blue last week he told me that the ultrasound came back with severe fatty liver evident. going for a fibroscan this week to see level of liver impact/disease. I asked what he thought caused it. But he said he didn’t know. Then I start looking into Truvada/PreP and suddenly see now that elevated liver enzymes, fatty liver disease and NASH are known side effects of these drugs. During all my discussions with true PreP clinic it was never mentioned as a risk - it was all about kidneys and bone. Really worried now that I have damaged my liver. What are peoples experiences? Could it be a coincidence and nothing to do with the PreP or ? concerned Irish!
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Leathercouple joined the community
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Any new updates on this? Particularly interested in the implications of taking proton pump inhibitors (Nexium) and/or Antacids.... I take such meds daily with my prep (generic Trucada). Worried.
