Longtime lurker here sorry for the long post. I have been on PrEP for almost 9 months. Trying to decide if Truvada could be responsible. I'm so exhausted/achy in lots of places/icky and keeps getting worse (could never have the energy for a job at this point its that bad). I don't even feel like the hassle of sex lately. Also since being on Truvada I have had unexplained weight gain of 25 lbs. (and was quite overweight before that). I also swear that on Truvada alcohol affects me much more and less pleasant. Btw, I have been on other meds for blood pressure a longtime.
My old doctor had been trying figure this out but I lost her and have seen a nurse practitioner who ordered lots of tests (she's not familiar with PrEP) everything so far comes up negative. Normal metabolic panel - liver, kidney, blood counts; thyroid, Stds, B12, borderline low D treating, testosterone, EKG. All normal including my total cholesterol though odd in past been at around 200 this time came in at 128. The new nurse basically doesn't have any ideas what to try/consider, does anyone here?
I have read its rare but seems there is a separate test for lactic acid which to knowledge has not been run is that worthwhile though I see weight loss with that? Would it show up in any other counts? Any ideas?
Thinking about taking a break from Truvada (never missed a dose so far). Last sex was 40 days ago so should be good on risk? How long if it's the problem to know it is or is not the Truvada, a few days, a week or (out of my system and feel better without it)? If I stop how long do you think I need to get back on it before risky sex?
Any ideas either related to Truvada or not would be helpful. Thanks.