Poppers and viagra

[barebackbro]

40 minutes ago, leatherpunk16 said:

This combo is lethal. My husband is dead because of this shit. He didn't know - and it wasn't until three years later I learned of his mixing the two. A boner pill plus Maximum Impact caused him to have a heart attack at a sex party. He survived that, but he was never the same after, and died two weeks later. 

To answer your question, I've been told it's 48 hours apart.

Hi @leatherpunk16.

I'm very sorry to hear this. I'm sure all members will be. 

I hope this thread hasn't been too difficult.

[BBSMKR]

1 hour ago, BootmanLA said:

I think you may misapprehend how Viagra (and Cialis) work. They increase blood flow to the penis, enabling it to get and stay harder than it would otherwise. They work by relaxing certain cells in the penis, which allows more blood flow through the vascular system, which then makes for a harder erection.

Poppers work by directly dilating blood vessels AND by relaxing certain muscles - for a bottom, it lets a top enter more easily. But if you already have increased blood flow to the penis from Viagra/Cialis, and then you use a vasodilator, which dilates blood vessels all over, the combination can produce a serious drop in overall blood pressure.

If used WITHOUT vVagra or Cialis, at least in some cases, the increased dilation of the blood vessels in the penis can make it harder (very short term) even though over the course of the session, especially with repeated hits, the effect is likely to be negated by blood flow dropping elsewhere in the body. So a single hit or two of poppers (for a top) MAY (and I stress may) have a net plus effect for fucking. Repeated use is likely to result in a limp dick.

Great summary, I’m a big poppers fan, I masturbate with them, I bottom with them and yes top with them, I just feel sexy using them. Of course I don’t need them, but in the line up of sex drugs they’re pretty harmless. Very rarely I have lost a boner on them, but nothing that 10 minutes of fresh air can’t fix. I appreciate everyone is different!

[Pozguyinchi]

14 hours ago, leatherpunk16 said:

This combo is lethal. My husband is dead because of this shit. He didn't know - and it wasn't until three years later I learned of his mixing the two. A boner pill plus Maximum Impact caused him to have a heart attack at a sex party. He survived that, but he was never the same after, and died two weeks later. 

To answer your question, I've been told it's 48 hours apart.

Sorry for your loss. I don’t use Ed meds but love poppers. 

[skinster]

23 hours ago, leatherpunk16 said:

This combo is lethal. My husband is dead because of this shit. He didn't know - and it wasn't until three years later I learned of his mixing the two. A boner pill plus Maximum Impact caused him to have a heart attack at a sex party. He survived that, but he was never the same after, and died two weeks later. 

To answer your question, I've been told it's 48 hours apart.

This is coming out as a longer post, but it's not all rant.

You know, in my experience (and I am not a medical professional of any viable qualification but I've been around blocks I could have avoided), there quite frequently are other contributing factors that people don't always register. Sometimes symptoms are hard to notice in the moment if you are not fully aware what to look for to help yourself and avoid the more severe scenarios. It is not only Viagra and poppers that come out to play. There is a lot that can fly under the radar, and most of it you may not even think twice about.

In general there is a long list of meds, supplements, over-the-counters and prescriptions that influence your blood pressure to go (1) up or (2) significantly down. Seasonal circumstances and remedies can contribute to the picture. That is before ED meds are added to the mix that you try to polish up with a case of poppers. Be mindful how much you actually take in a mix and what is currently in your system, as different things take varied time to wash out. It is not short by most means, and that is speaking out of personal experience.

Keep in mind - nobody knows your body better that you. And nobody else should be in that position instead of you to make a decision. And unfortunately, with age you may have to make more of such decisions without being asked.

(1) Common pain medications (OTC NSAIDs), anti-inflammatories (prescribed and herbal/therapeutic supplements), cold-and-flu medicines (especially with decongestants), allergy meds (especially with Pseudoephedrine for decongestant), antidepressants, (even legal Ephedra and Ginseng) stimulants including caffeine - all contribute to incrementally higher blood pressure. If you habitually mix them without looking - you may be asking for trouble down the road.

Being dehydrated was the most difficult thing for me to pick up on - that also does raise your BP, starves you of oxygen but manifests itself very lightly. When playing, it is very easy to overlook the symptoms. Including if you're in a new climate when traveling.

(2) HBP pills, with many classes within them, significantly knock down the blood pressure as designed, and commonly have the frowned upon ED side effects. You should not take anti-hypertensives close to taking ED medications pretty much in any combination. Discuss it with your physician. Better if you have tested yourself well before playing how long it actually takes for your body to react to interruption in HBP meds (and any other prescription) to raise your blood pressure to again need the pills. Could be several days. Throughout that time your body will have a varied damping effect on boner pills.

Mixing BP uppers and downers is the worst kind of negligence you can do to yourself regardless of dosage. If you don't know what dehydration feels like (and it's not about feeling thirsty) - you're not helping yourself either. It took me personally a long time to figure out the mixtures and effects as I've literally started with a info blindfold mixing many things at the same time. That ignorance is not the one that is bliss. I've landed to ER once (early on), and I've done some back and forth since selecting better therapies and trying to reduce side effects. I've kept ED meds, I've ditched HBP meds with the help of a change in diet. My physician was receptive to my notes. I own an oximeter - I can check my pulse when I need to.

And I always drink extra water when I play but I do not share bottles.
Take care of yourself.

[Close2MyBro]

1 hour ago, skinster said:

(2) HBP pills, with many classes within them, significantly knock down the blood pressure as designed, and commonly have the frowned upon ED side effects. You should not take anti-hypertensives close to taking ED medications pretty much in any combination. Discuss it with your physician. Better if you have tested yourself well before playing how long it actually takes for your body to react to interruption in HBP meds (and any other prescription) to raise your blood pressure to again need the pills. Could be several days. Throughout that time your body will have a varied damping effect on boner pills.

Mixing BP uppers and downers is the worst kind of negligence you can do to yourself regardless of dosage. If you don't know what dehydration feels like (and it's not about feeling thirsty) - you're not helping yourself either. It took me personally a long time to figure out the mixtures and effects as I've literally started with a info blindfold mixing many things at the same time. That ignorance is not the one that is bliss. I've landed to ER once (early on), and I've done some back and forth since selecting better therapies and trying to reduce side effects. I've kept ED meds, I've ditched HBP meds with the help of a change in diet. My physician was receptive to my notes. I own an oximeter - I can check my pulse when I need to.

And I always drink extra water when I play but I do not share bottles.
Take care of yourself.

If you're on High Blood Pressure medication and it's affecting your ability to get and/or maintain an erection, I'd strongly suggest you talk to your doctor. There are numerous different blood pressure medications they can try and one may work better for you than another. My father was an alcoholic. He was put on BP medication but refused to take it when the BP medication and alcohol made him sleepy and he enjoyed drinking too much so he quit taking his blood pressure medication. He suffered kidney damage because of the uncontrolled high blood pressure and had to go on dialysis. The sad part of this story is that they could have changed his blood pressure medication and he would have been able to continue to drink (not that it would have been good for him) and not ended up with irreversible kidney disease.

When I was put on blood pressure medication, I had side effects from the first one they tried. I let the doctor know and he changed me to a different class of medication, and I've had no issues with it since. I don't have any side effects and it doesn't stop me from doing anything, so the first medication may not be the right medication for your body.

[skinster]

2 hours ago, Close2MyBro said:

... I don't have any side effects and it doesn't stop me from doing anything, so the first medication may not be the right medication for your body.

You're right. Professional medical advice that is followed is paramount. My dad was similar to yours and a heavy smoker to boot well aware of his HBP issues. Peer pressure in the end did not have enough effect, and he didn't recover from his first stroke. Died a week after when probably could have gone for years more.
I've been through several HBP class types myself and wasn't too happy with either one. Side effects were more than just one, as I am listing ED affects on here only for the sake of discussion.

Additionally, I've come to realize that just because there is a pill for whatever, you don't have to take or rely on it - it came with time and back-and-forth experience. I would rather NOT take ANY pill unless there is no other way around it. And with HBP I found a way to maintain it without any medication, with or without side effects. Plus some self-education along the way. Win-win in my understanding. Just like knowing not to heavily mix ED meds with poppers, even good poppers. I like a whiff here and there but I won't pore it down my gas mask. I hope there are more people around paying attention to such things these days.

[BootmanLA]

15 hours ago, DumpUrPOZinDEEP said:

Cialis is not the same drug and it is safe to take with poppers

The first half of that sentence is true: Cialis is not the same drug as Viagra.

The second half of that sentence is false.

From drugs.com ([think before following links] https://www.drugs.com/tips/cialis-patient-tips)  :

"May interact with some medications including nitrates - use of Cialis and nitrates is contraindicated because of the severe hypotension that can develop. "  Poppers are frequently nitrates or nitrites or related compounds (and usually there's no way to know exactly what's in the particular brand/bottle, even from one to the next).

From the Mayo Clinic ([think before following links] https://www.mayoclinic.org/drugs-supplements/tadalafil-oral-route/side-effects/drg-20067204?p=1)  :

"Do not use this medicine if you are also using riociguat or a nitrate medicine, often used to treat angina (chest pain). Nitrate medicines include nitroglycerin, isosorbide, Imdur®, Nitro-Bid®, Nitrostat®, Nitro-Dur®, Transderm Nitro®, Nitrol® Ointment, and Nitrolingual® Spray. Some illegal ("street") drugs called "poppers" (such as amyl nitrate, butyl nitrate, or nitrite) also contain nitrates. If you need to use a nitrate medicine, take it at least 48 hours after your last dose of tadalafil."

From Healthline.com ([think before following links] https://www.healthline.com/health/are-poppers-safe#risks)  :

"Poppers can interact with other drugs, particularly medications used for erectile dysfunction (ED), such as sildenafil (Viagra) or tadalafil (Cialis). Like poppers, these medications cause a drop in blood pressure. Used together, poppers and ED medications can lead to stroke, heart attack, or death."

I could go on and on, but the point is clear: the medical literature is replete with warnings about this. You're free to ignore those warnings if you wish, and if you do, you may well not have any side effects. That sort of navel gazing does not miraculously become sound medical advice in general.

[viking8x6]

@BootmanLA , thanks for your clear explanation. The above post also applies to vardenafil (Levitra) - and yes, if you're curious, its labeling information also specifically includes warnings against using it with alkyl nitrites (poppers).

For those who want to know about the timing, you can use Levitra and Viagra up to 24 hours before poppers, and Cialis up to 48 hours before poppers, without worrying about the interaction (i.e. don't use them closer together than that). Here's the applicable research for Cialis: [think before following links] https://pubmed.ncbi.nlm.nih.gov/14642699/

On the other hand, you can use poppers before any of these three drugs as close to them as half an hour without worrying - poppers are very volatile and clear the system rapidly. Here's the research paper for that: [think before following links] https://pubmed.ncbi.nlm.nih.gov/10725305/

[BannedWord]

On 6/14/2022 at 6:16 PM, skinster said:

(2) HBP pills, with many classes within them, significantly knock down the blood pressure as designed, and commonly have the frowned upon ED side effects. You should not take anti-hypertensives close to taking ED medications pretty much in any combination. Discuss it with your physician. Better if you have tested yourself well before playing how long it actually takes for your body to react to interruption in HBP meds (and any other prescription) to raise your blood pressure to again need the pills. Could be several days. Throughout that time your body will have a varied damping effect on boner pills.

This is definitely true from personal experience. I needed to do a cardiac catheterization a couple years back, and as part of the lead-up work, along with my regimen of prostate meds, Cialis (using for the prostate indication), and HBP meds, my cardiologist threw in a vasodilator to test. Along comes a vasovagal reaction which sent my BP down significantly and instantly into pass-out range. I understand only a bit about how poppers work, but they're contraindicated for anything to do with the Big-3 ED drugs. 

[think before following links] https://www.mayoclinic.org/drugs-supplements/amyl-nitrite-inhalation-route/side-effects/drg-20061803?p=1

Since I'm normally prone to vasovagal reactions from stress and extreme exertion (not running marathons in my future for a lot of reasons, heart valve leakage congenitally being just one), I'm pretty sure I'll heed the warnings.