Also, be aware that there were few to no transguys involved in the study, so most transdude-specific recommendations are extrapolated from observations about effectiveness in women - which may not be quite conservative enough, considering the nature of hormonal differences - and that's as clinical as I want to get, because i'd rather be breeding your hot boy holes, but:
- Studies seem to indicate that it can take 21 days to reach full tissue effectiveness levels in vaginal tissue
- Even then, concentrations seem to stay high for less forgiving periods, so don't miss a single day - it's less forgiving
There are the recommendations my favorite transguy fuckhole was given.