Jump to content

barefootbob

Members
  • Posts

    307
  • Joined

  • Last visited

Everything posted by barefootbob

  1. I'm a bottom and it just plain feels better raw than wrapped. nothing like skin on skin
  2. my first man to man, I was 14 he was 18, I bottomed for him for about 6 months until he left for college.
  3. I'm 55 and Asian guys don't put any zipitty into my doodah, nothing against the race I just don't find the guys attractive. I am partial to hispanic guys and many guys around my part of the US don't. so it is a preference
  4. I have one that we hook up from time to time, I have to play with his nips for 45 minutes then get a less than 5 minute fuck, always the same way, me facedown. hey at least I am getting some
  5. I was brought up in this nasty, evil, vile cult called church of christ. in my early teens I started asking "why" why certain things happened the party line answer they kept giving "it is gods will. don't question it". after about a year, I quit asking and stopped believing. I still had to go to church to keep the peace but I was going through the motions until I graduated high school and went into the USAF and told those sorry motherfuckers to kiss my ass.
  6. there are several on HGTV and not just the gay ones; the guy on Income Property cums to mind
  7. I know where you are coming from, I'm 55 and neg butt it is damn near impossible to find tops that want to fuck mostly because I live in a college town with pleanty of available young studs. for now I "need" to stay neg because of the nature of my job, being in an at-will state one can be fired for ANY reason. if it does happen, then I'll deal with it
  8. for those who think it is gross, what's the difference in rimming and sucking cock that has been in your ass?
  9. damn straight barer (no pun intended LOL), my pussy is just that - a sexual orifice for a top to fuck and get his pleasure.
  10. I would love to be fucked by a little person (midget) or two.
  11. For me it depends on the feet, if I find them hot then I can endure however bad they stink, worshiping them, licking them clean
  12. This could be hopeful. A powerful topical preventative for HIV, the virus that causes AIDS, could soon be in the works thanks to a newly discovered molecular compound that research at Texas A&M University and the Scripps Research Institute shows dissolves the virus on contact. The ability of the synthetic compound known as “PD 404,182” to break apart the AIDS-causing virus before it can infect cells was discovered by Zhilei Chen, assistant professor in the university’s Artie McFerrin Department of Chemical Engineering, and her team of researchers. Their findings appear in the November online edition of “Antimicrobial Agents and Chemotherapy,” a journal of the American Society for Microbiology. “This is a virucidal small-molecule compound, meaning that it has the ability to kill a virus; in this case that virus is HIV,” Chen says. “Basically, it acts by breaking the virus open. We found that when HIV comes in contact with this compound, it breaks open and loses its genetic material. In a sense, the virus ‘dissolves,’ and its RNA becomes exposed. Since RNA is pretty unstable, once it is exposed it’s gone very quickly and the virus is rendered non-infectious.” In other words, the compound works by quickly ripping open the virus before it can inject its genetic material into a human cell. What’s more – and perhaps even more important -– the compound, Chen explains, achieves this by acting on something within the virus other than its viral envelope protein, meaning that the virus can’t alter its proteins to bolster its resistance -– something that’s made HIV notoriously difficult to treat. “We believe this compound is not working on the viral protein of the viruses but on something else common in all the viruses on which we tested it -- some cellular material common in these viruses,” Chen notes. “Because this compound is acting on a component that is not encoded by the virus, it will be difficult for the virus to evolve resistance against this compound.” While not a cure for HIV, the compound demonstrates significant potential for use as a preventative, specifically in the form of a topical gel that could be applied in the vaginal canal, Chen explains. “We conducted a number of tests to demonstrate that this compound remains active in vaginal fluid and is not rendered ineffective,” Chen says. “In the form of a vaginal gel, the compound would serve as a barrier, acting almost instantaneously to destroy the virus before it could infect a cell, thereby preventing HIV transmission from one person to another.” Surprisingly, Chen and her team did not set out to discover an HIV preventative. Instead, they were conducting screenings of molecules for use in potential drug therapies targeting hepatitis C virus, which causes the dangerous and often fatal disease of the liver. Employing a screening system developed by Chen, the team screened thousands of molecular compounds, in search of those that could block aspects of the HCV life cycle. During the course of the screenings, the team made an interesting discovery: Not only was PD 404,182 an HCV inhibitor, it also worked on lentiviruses (the group’s negative control in its experimental procedures). Intrigued by that finding, Chen then tested PD 404,182 on HIV, which itself is a lentivirus and found the compound to be even more effective on HIV than on HCV. “We believe PD 404,182 acts through a unique and important mechanism,” Chen notes. “Most of the known virucidal compounds interact with the virus membrane, but our compound does not appear to interact with the virus membrane. Instead, it bypasses interaction with the membrane and still compromises the structural integrity of the virus.” The ability of the compound to avoid interaction with the virus membrane is important because human cells have similar membranes, Chen notes. If the compound were to disrupt the structure of the virus membrane, it could also disrupt and ultimately kill human cells. PD 404,182 doesn’t interact with these membranes and is therefore a more attractive option for clinical treatment, Chen says. As is the case with any potential pharmaceutical, several key steps are still needed before it winds up on drug store shelves. In addition to several rounds of animal studies to ensure the compound is safe for humans, further collaborations with chemists are needed to continue to improve the efficiency of the compound. Chen says. What’s more, Chen also plans to further explore the mechanism by which PD 404,182 breaks apart HIV. This work is collaboration between Chen’s team, consisting of graduate students Ana Maria Chamoun and Rudo Simeon, postdoctoral associate Karuppiah Chockalingam, and Professor Philippe Gallay’s team at the Scripps Research Institute.
  13. my oldest was 73 when I was 20, so almost the same age gap as you. we met at a mutual friends house for a party, there were lotsa hook ups going on. I was only in my shorts, at the time I was 5'10" 120 lbs, we chatted a bit; he telling me how cute I was while his hands roamed all over my body. They eventually ended up carassing my ass crack causing me to emit an uncontrolable moan. His pants were tented and I knew where this was headed. he grabbed my hand and we went to a corner of the room where we started making out. to cut to the chase, he removed my shorts, dropped his pants, put my legs on his shoulders and fucked me, dropping a load up my pussy. That night I also got fucked by an older guy of 35. LOL so the oldest was 72, 52 year age gap
  14. I like this position also. I got fucked this way by a guy that was about 7 inches shorter than me so I had to really spread my legs to give him access to my hole. This put me a bit off balance giving him the ability to grab my hips and control the fuck much more so than if he were my height. I could reach the floor with my palms and give a bit of stability but when he really started to pound me it became more difficult. After he dumped his load in my ass it was an easy transistion to get on my knees to suck him clean.
  15. the last time I was on gay.com, it was the same way . . you chat away for 30 +minutes, then just when you think it is all said and done with a hook up coming the other person exits chat. you wait for a while just in case he lost connection but he never comes back. the college station room was really bad about that, that is when you could actually get people to chat.
  16. I guess I should have added, I am blonde myself. :-)
  17. WQUOTE=yunghungtop;36010]Some of us get off on domination, and sex where tops use and disrespect bottoms. I'm a top that likes it that way. The bottoms I fuck like it that way. How the fuck does that concern you? Well said, Master Yunghungtop. I have one top who makes love/has sex with me and another top who fucks me. The difference? The first top respects me as a person whereas second top uses for his own end, degrades me and just does what he wants. Each has his own needs and wants - which I fullfill to the end. Truth be told, I prefer the second top.
  18. Was the guy blonde? This was the funniest story I've ever read here and very well written. I could picture the entire thing in my mind's eye.
  19. I am there for the tops pleasure ONLY, my pleasure is of no consequence, my entire focus is the top and getting him off.
  20. I love funk 'n go, no cuddling, no kissing, no holding. just fuck my ass, cum and leave if that is what you are after.
  21. Dirtysouth, your weight/size is not/would not be a problem for me; you have cock, you get hard, you fuck ass, what more does a bottom need. I am 5'10" 160, total bottom, in decent shape but I can't get it up/hard which turns most guys in my area off, even if they are totaly horned out they don't want to hook up. I also have a genetic condition called neurofibromatosis which has lots of bumps on my chest, back and legs, if the lack of getting hard isn't a problem one look at the NF is. (hence the reason for no pic on the profile). I believe the NF is the cause of me not getting hard which has been the case since I was in my mid 20's, the NF showed up in my early 20's. sorry, I didn't mean to highjack the thread, it is I can understand where you are coming from.
×
×
  • Create New...

Important Information

By using this site, you agree to our Terms of Use, Privacy Policy, and Guidelines. We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.