Second Confirmed Case Of Hiv Acquisition While On Prep

[rawfuckr]

All details here

 

http://www.thebody.com/content/78607/despite-second-case-of-hiv-prep-still-most-effecti.html

 

TLDR

 

• Guy claims 100% bare top (condoms with partner when bottom)
• Partner +UD
• comfirmed he didn't get it from partner.
• claims to have had only two other partners from where he acquired HIV. He was 100% top with them
• HIV strain he got has resistance mutations for most of the nucleosides and some NNRTIs [non-nucleoside reverse transcriptase inhibitors]
• adherence tested through hair samples and dry blood spots

 

developing story ...

Edited October 19, 2016 by rawfuckr

[drscorpio]

It sounds very similar to the first case. Truvada will not protect you from a strain of HIV virus that is Truvada Immune/Resistant. 

[hungryhole82]

Is there

 

It sounds very similar to the first case. Truvada will not protect you from a strain of HIV virus that is Truvada Immune/Resistant. 

According to avert.org, in USA most HIV patients have HIV-1, Group M, Subtype B strain.  Gilead should do more R&D and find out which strains Truvada immune to. 

[punaman]

Makes sense. Kind of like the Partner Project Study, the only negs who contracted HIV in a mixed serosorting relationship is when they strayed out of the relationship and had bare sex with anons. 

[topstud127]

To get it while topping is also interesting

[Guest PozGoat]

I want that fucking strain pumped up my ass, deep.

[bearbandit]

From what I've read about this, the guy's virus has two specific mutations which make it resistant (but not totally resistant) to tenofovir. I've seen the list of drugs his virus is resistant to and it's about 10 (mostly, if not all, NRTIs and NNRTIs). Once analysed, we know which mutations will make HIV resistant to which drugs,so it's not a question of Gilead pulling their fingers out.

It's important to remember that resistant/mutated virus is weaker than wildtype virus, and ultimately mutated virus is overtaken by wildtype virus, which is how come resistance fades over time and drugs can be re-used.

While it's always been known that getting assfucked bare is the commonest infection route, it's always been known that the guy fucking can get it: how else do hundred percent hetero guys get it sexually from women?

For this to happen twice in a year is still within the expected efficacy of truvada as PrEP. While on an individual level of course it's a bloody disaster, but on a total population level, it's unsurprising and truvada is as near to total protection as you can get. If I were neg and on PrEP I wouldn't be worried on a personal level: all manner of things are still more likely than seroconverting while on PrEP.

apologies for any typos - writing this in bed and my tablet's dictionary isn't as versatile as the PC's...

[ChargedLoadLover]

I want that fucking strain pumped up my ass, deep.

Fuck yes, me too.