Is it safe to mix poppers, weed and alcohol?

[Openmouthpolicy]

I’ve tried poppers and weed and it’s amazing especially when I am going for a long cum dump session and taking loads all night, be it at a bath house or at a sex club. I’ll take an edible and do some popper hits and use my toys at home to get me loose and in the mood before I head out to a bath house or sex club to let anyone and everyone breed me usually I wear a blind food too. I’ve been curious though about mixing in the feeling of being slightly drunk too. Any tips on this? Is it terrible unsafe? (Yeah I know the other things are unsafe too but you know what I mean.) does it make people really sick? What does it feel like? I wanna be mostly relaxed and happy and slightly out of it and even maybe brown out here and there while I get bred all night. Any thoughts? 

[ErosWired]

If you’re asking whether they’ll chemically interact to pose a physical risk to your body’s systems and potentially harm or kill you, there’s not a particular known health risk such as there is in mixing poppers with Viagra.

But otherwise, of course it isn’t safe. Both alcohol and cannabis can impair your judgment, both alcohol and poppers can cause you to lose consciousness, and any combination of the three is likely to compound the chance that you’ll use too much of them, lose control of yourself and your situation, and thereby put yourself at risk.

You want to cumdump - blindfolded - whilst drugged up to the point that you’re falling in and out of consciousness while completely vulnerable to any and every man on the premises who could do anything at all to you? No, it isn’t safe. In fact, if that’s what you’re planning, asking whether the drug combo will make you sick is kind of silly. You’re at worse risk of falling, hitting your head and getting a concussion, asphyxiating on your own vomit, or having your anus torn from having something shoved up it while you’re unconscious.

[chasingseedinaus]

I've mixed them before. I would be careful with it. Better to just keep it to weed and poppers.

[EuRawBull]

Weed compounds amplify the effects of alcohol and poppers.

There is a long standing rhyme which actually seems to be backed by scientific consensus: "Beer before grass, you're on your arse; grass before beer, you're in the clear."

Doing poppers while you are still high on weed will have different effects if ingested or inhaled. If ingested, weed will have a marginal effect on poppers. If smoked, weed will increase 3 fold the effect of inhaling poppers for the duration of the high. 

I strongly suggest you stick with just two at the time of the combo. While your body may respond well to the 3-combo, there is no rule to say that next time it will be the same. Remember that we only have half-assed evidence on how the 3-combo behaves for everyone. It also depends on how much and the strenght of the weed you smoke, how potent the poppers are, how much alcohol are you ingesting, your body weight, your age, blood pressure and so on. 

Anecdotally, the weed our parents and grand parents smoked in the 60s to mid 90s was 4 to 10 times weaker and less THC than we have today. Some strains of weed can these days be used to propel Elon's racket X - they are that strong!

I do use weed and poppers myself. I grow the weed and for poppers I stick to amyl. Not too much, but just enough to give you a buzz. 

And I also want to reiterate what others have said: better to be conscious at all times. While the fantasy of being a cum dump fucked by anyone and loaded by gallons of fresh cum is exhilarating, there is a high chance that something can go wrong and you end up impaired for the rest of your life.  I am personally a very risk adverse cum dump and mindful top. 

If I top, I am always alert on the signs I get from the guy I fuck: twitches, hole tightening, limp arms and legs, etc. I am also careful with my bottoms that they don't hit their head, twist their body in pain, or similar.  If I bottom, I listen to the pleasure and pain of my body: from the outter rim of my hole to the inner sphincter I am in touch with reality at all times. Even if I do weed and poppers I never go past the limit and threshold. It takes a bit of discipline to listen to your body, but if you do that you end up with awesome experiences. 

 

[ErosWired]

11 hours ago, EuRawBull said:

If smoked, weed will increase 3 fold the effect of inhaling poppers for the duration of the high. 

If that is indeed the case, then that would seem to me to argue strongly against doing it. A threefold increase in the effect of poppers could easily put someone over the line into blacking out, or having a blood pressure drop to a dangerous level. And if it were a Top doing it, he could forget about an erection. (Last week I had a Top who came armed with no fewer than 3 (!) bottles of poppers and a bottle of lube. Every thirty seconds or so he’d drip a little more lube on my ass and take another hit of poppers. Lube-poppers, lube-poppers, lube-poppers, over and over…because he lost his hardon after the first three minutes and spent the next hour trying to rub himself hard in the cleft of my ass under the influence of poppers. Hopeless situation.)

[TallAussieBtm]

Used to love transitioning from one to another when going to major all night dance parties. "Three kinds of out of it", I called it! Quick onset alcohol until edible THC kicked in. Then when that wore off an e to get deep into the groove through the night. Minimal poppers but definitely some for those peak moments. No particular interactions I can think of but each can be a bit overwhelming at times. Best enjoyed staggered IMHO, rather than all at once! Many years since I did this, though! 🕺😃

[tallslenderguy]

Not a simple question and there is no black or white answer.  Both marijuana and alcohol affect cognitive and motor function.   The more you take, the more you mix, the greater the (presumably wanted) effects and (unwanted and deleterious) 'side' effects.  

Further complicated by the differences of potency and effects of different types of cannabis and different means of getting it into the body (e.g., smoking, eating), frequency, amounts... so many variables. 

Same with alcohol. Are we  talking beer or tequila shots? Or everything in between. Again, type and quantity all factor in. 

Poppers (amyl or butyl nitrite) are vaso dilators (so are ED drugs like viagra). I.e., the sought after effect is the warm/sexy/fuzzy rush resulting from pretty much instant vasodilation.  They were the original 'nitro' intervention for people having heart attacks. Biggest side effect is a drop in blood pressure (related to vaso dilation). Our organ systems (e.g., brain, heart, kidneys, gut, liver, etc..) require a particular ongoing mean arterial pressure (MAP >65) in order to function and stay alive.  When  someone comes into the hospital with sepsis, our first concern is not the pathogenic infection but the resulting drop in BP from the infection. That ongoing drop will cause organ system failure and death, and that can happen pretty fast if not addressed.  

Poppers are not sepsis though. Their effects are pretty instant, but only last ~2-5 minutes.  But then, just like cannabis and alcohol, 'dosing' factors in.  Big difference between taking a hit a 3 or 4 times while fucking and wearing a gas mask with a continuous feed or taking a hit every minute  while the effects of the prior hits have not worn off. 

So, one can see the challenge to answering the question?  i did a study search on mixing THC with Nitrites, didn't find any evidence based/study info. But THC and Nitrites affect different physiological components.  Sort of like asking, is it safe to mix drinking/marijuana/poppers with using a chain saw, or turning on a faucet.  You might get away with both without harm, or you might not. 

[Openmouthpolicy]

I recently took about a 10mg edible and had one stuff jameson and gingerale and got fucked all night long by tons and tons of dude and did poppers all night.. it was amazing but I def feel that I didn’t need the alcohol in the end. I def do poppers all night long because usually when I cum dump iam doing for for hours and hours. I don’t do them every minute though. I’d say about 3-5 times in a fuck session with a guy but again sometimes it’s like 30 guys. I always feel fine physically but I do wonder if I am doing it too much? I feel fine the next day mostly and try not to take crazy huge hits and I usually let the effects of the last hit wear off before I go again. Most times at least. Does this seem too much? 

[BootmanLA]

On 11/2/2023 at 11:02 AM, tallslenderguy said:

Poppers (amyl or butyl nitrite) are vaso dilators (so are ED drugs like viagra).

Not quite the case. Poppers are vasodilators, but ED drugs (Viagra, Cialis, etc,) are actually a different class of drugs entirely called PDE5 Inhibitors. Rather than dilate the veins (which poppers do), they work by enhancing the effect of nitric oxide on the muscles of the penis. When a penis gets that influx of nitric oxide, the muscles in it relax, which allows blood to flow into it, causing the erection. Rather than the medication dilating the veins (again, what happens with poppers), the relaxed muscle allows increased blood flow to expand inside the veins. So rather than a loosened vein with improved flow, the ED drug helps the vein fill itself and harden the penis.

That's why poppers so often cause a top to lose his erection, while ED drugs (typically) improve it. And it's why they're dangerous together: the vasodilator in the poppers keeps trying to expand the veins (not just in the cock but everywhere), which causes a drop in blood pressure. If you further relieve the pressure on the veins in the penis by relaxing the muscles around them (giving them more room to expand, the veins can lower pressure over the body so low that you can have a BP "event".

[ErosWired]

18 hours ago, BootmanLA said:

That's why poppers so often cause a top to lose his erection, while ED drugs (typically) improve it. And it's why they're dangerous together: the vasodilator in the poppers keeps trying to expand the veins (not just in the cock but everywhere), which causes a drop in blood pressure. If you further relieve the pressure on the veins in the penis by relaxing the muscles around them (giving them more room to expand, the veins can lower pressure over the body so low that you can have a BP "event".

And by “dangerous together” he means “potentially fatal”.

[Guy4GuyCoSpgs]

I've done poppers and alcohol with no problem. 

[tallslenderguy]

It's true that drugs like sildenafil cause vasodilation differently than amyl or butyl nitrite, but both are still vasodilators. 

"Sildenafil acts as a selective inhibitor of cycle GMP-specific phosphodiesterase type 5, resulting in smooth muscle relaxation, vasodilation, and enhanced penile erection. The vasodilating action of sildenafil affects both the arteries and the veins.5

 

Reported side effects in the normal healthy population are usually associated with vasodilation. These include headaches (16%), flushing (10%), rhinitis (4%), dizziness (2%), hypotension (<2%), and postural hypotension (<2%). Other side effects include dyspepsia (7%), blue-green color-tinged vision and blurred vision (3%), and an unexplained myalgia.3,4

Although their incidence is small, serious cardiovascular events including significant hypotension can occur in certain population at risk. Most at risk are individuals who are concurrently taking organic nitrates.4"

[think before following links] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437061/

 

[BootmanLA]

9 hours ago, tallslenderguy said:

It's true that drugs like sildenafil cause vasodilation differently than amyl or butyl nitrite, but both are still vasodilators. 

"Sildenafil acts as a selective inhibitor of cycle GMP-specific phosphodiesterase type 5, resulting in smooth muscle relaxation, vasodilation, and enhanced penile erection. The vasodilating action of sildenafil affects both the arteries and the veins.5

 

Reported side effects in the normal healthy population are usually associated with vasodilation. These include headaches (16%), flushing (10%), rhinitis (4%), dizziness (2%), hypotension (<2%), and postural hypotension (<2%). Other side effects include dyspepsia (7%), blue-green color-tinged vision and blurred vision (3%), and an unexplained myalgia.3,4

Although their incidence is small, serious cardiovascular events including significant hypotension can occur in certain population at risk. Most at risk are individuals who are concurrently taking organic nitrates.4"

[think before following links] [think before following links] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437061/

 

I *believe* the vasodilation is an indirect effect from the relaxation of the muscles around them, rather than a direct expansion of the veins themselves (ie a true vasodilator).

Put another way, something can have the effect of dilating *specific veins* without being a *vasodilator* in general - and in fact PDE5 inhibitors like Viagra and Cialis work by relaxing only certain muscles of a particular type - the spongy kind in the penis (and in parts of the lung). The dilation of the veins in the penis as a result is because of the increased blood flow allowed by the muscle reaction, not because the veins *themselves* are being expanded (as is the case with a true vasodilator).

Vasodilation (the effect) is not just caused by vasodilators (the class of drug), but by other things that allow vasodilation to occur.

[BootmanLA]

9 hours ago, Guy4GuyCoSpgs said:

I've done poppers and alcohol with no problem. 

Some people have done all sorts of things "with no problem" on that particular occasion. All warnings of this sort are generalized and may not apply in every case. Your success with taking both in the past does not mean you or anyone else may not have a problem mixing them in the future.

[tallslenderguy]

11 hours ago, BootmanLA said:

I *believe* the vasodilation is an indirect effect from the relaxation of the muscles around them, rather than a direct expansion of the veins themselves (ie a true vasodilator).

"The blood vessels in your body aren’t just tubes that stay the same size all the time. Blood vessels also contain muscle, and that muscle controls just how wide or narrow your blood vessels are at any given time. When blood vessels get wider, that’s vasodilation. The opposite process, when blood vessels constrict and get narrower, is called vasoconstriction."

[think before following links] https://my.clevelandclinic.org/health/diseases/23352-vasodilation