Poppers tolerance

[GexTrick]

I've been into poppers for 3 years now, which makes me consider myself a relative newbie at it (at least compared to guys whom has been sniffing for many many years).

I still remember my first bottle (Everest premium) cause it gave me a hit so strong at first I actually got a bit scared by the strong dizziness and the bumps of my heartbeat drumming in my head, but i was soon hooked.

Throughout time I tried many brands, not using them every day but let say on average a bottle a month concentrating the use in 4 or 5 bathhouse/sex club or home bating sessions.

The problem is, expectedly, my body built up a tolerance with time and although the sensation is still overall nice it's nowhere near the intensity it was in my early uses.

I was wondering: can this tolerance be at least reduced after a some time without use? And if so, what would be, on average, a reasonable time of non use to achieve it?

Do someone know tricks to cheat my tolerance, such as constantly switching formulas (amyl, butyl, propyl and mixed formulas)?

[Guest]

@GexTrick very few experiences in life have the same strength and powerful sensations as when you do it for the first time. 

Poppers are no exception, however after two or three weeks I would expect the tolerance to subside and you can feel a strong sensation when you do it again. But it will not be like the first time. Close enough, but no cigar. Try to stick to amyl formulation if available in your area. The French ones are the best there are. Switching formulas won't achieve the rush you are after, unless there is some other strong shit mixed in there. 

The other option is to mix weed and poppers. Careful with the mix if you have any medical underlying conditions. But generally speaking, you can get a pretty good high when the two are mixed. Experiment at first in safe environment before doing it at a bathhouse / club. (i am not familiar with the Italian sex club scene so I can't recommend any establishments.).

[Guest]

In my experience, I build tolerance if I use more than twice a week. I also find that the intensity of the poppers decreases significantly after 3 bathhouse/long fucking sessions, so I’ll get a new bottle every 1-2 weeks. 

[11bi11guy]

Going a couple weeks without using generally resets my tolerance.

I switch it up within a single session between butyl nitrite (tends to open my external sphincter more, more of an immediate head rush) and amyl nitrite (tends to open me up deeper, slower full body rush).

Also, getting really good brands helps. I use Real Gold for butyl and Everest Premium (blue bottle) for amyl. I keep them fresh by storing them upside down and keeping any unopened backup bottles in the freezer.

[GexTrick]

16 hours ago, PollaDeMiel said:

@GexTrick very few experiences in life have the same strength and powerful sensations as when you do it for the first time. 

Poppers are no exception, however after two or three weeks I would expect the tolerance to subside and you can feel a strong sensation when you do it again. But it will not be like the first time. Close enough, but no cigar. Try to stick to amyl formulation if available in your area. The French ones are the best there are. Switching formulas won't achieve the rush you are after, unless there is some other strong shit mixed in there. 

The other option is to mix weed and poppers. Careful with the mix if you have any medical underlying conditions. But generally speaking, you can get a pretty good high when the two are mixed. Experiment at first in safe environment before doing it at a bathhouse / club. (i am not familiar with the Italian sex club scene so I can't recommend any establishments.).

So true, didn't hope to feel again like the early times indeed. Thanks for the advice

 

5 hours ago, 11bi11guy said:

Going a couple weeks without using generally resets my tolerance.

I switch it up within a single session between butyl nitrite (tends to open my external sphincter more, more of an immediate head rush) and amyl nitrite (tends to open me up deeper, slower full body rush).

Also, getting really good brands helps. I use Real Gold for butyl and Everest Premium (blue bottle) for amyl. I keep them fresh by storing them upside down and keeping any unopened backup bottles in the freezer.

Yeah, Everest are among the best I've tried so far, I want to try Everest premium ultra which is supposedly 90% pure amyl. Never tried real gold if memory doesn't fail me, will keep an eye open.

Didn't know about storing poppers upside down. Why so?

[11bi11guy]

5 hours ago, GexTrick said:

Didn't know about storing poppers upside down. Why so?

Fluid dynamics. Poppers go bad when they’re exposed to air (I think the chemical process is called oxidation). Storing them upright will leave a little pocket of air/fumes at the top, and no matter how hard you screw the cap on, there will be some air/fumes that get out and new air that gets in. Storing them upside down means the little pocket of air/fumes will now be at the bottom of the bottle, away from the cap and seal, with no chance for new air to get in.

[GexTrick]

4 hours ago, 11bi11guy said:

Fluid dynamics. Poppers go bad when they’re exposed to air (I think the chemical process is called oxidation). Storing them upright will leave a little pocket of air/fumes at the top, and no matter how hard you screw the cap on, there will be some air/fumes that get out and new air that gets in. Storing them upside down means the little pocket of air/fumes will now be at the bottom of the bottle, away from the cap and seal, with no chance for new air to get in.

Well seems like I've learned something new. Thanks

[KindaBasic]

As already stated, a break might help. The Leather Man in NYC has the legendary Brown Bottle that kicks my ass even when I’ve become desensitized to most brands. It used to be you could only by it in the store cash only. You can now get it Briarwalk.com.  It’s not the cheapest, but damn! 

[tallslenderguy]

Poppers (amyl nitrite) original use was to treat cyanide poisoning and for angina (chest pain from lack of blood flow to the heart)... so there is pharmacological info available. Here's some excerpts and a link from a site i use frequently (i'm a critical care nurse).  We use nitrite/nitrate based vasodilators all the time in the hospital. They work fast, but the effects only last a few minutes. If we are using a nitro patch, we take it off after 12 hours to avoid tolerance.

Another thought is your arteries may have changed over time (possible stenosis-i.e. narrowing,  could make the effects less dramatic- speculating). i also think there is a possible psychological effect. Same roller coaster we ride as a kid may not be as thrilling after the 1000th time as an adult? 

"Pharmacokinetics

Onset: 10-30 sec

Duration: 3-15 min (angina)

Peak: 3 min

Acute Relief of Angina

0.3 mL by inhalation of crushed ampule, may repeat q3-5min

Wave crushed ampule under nose multiple times for 2-6 nasal inhalations

Cyanide Poisoning

0.3 mL ampule crushed and contents poured onto a gauze and placed in front of patient's mouth or endotracheal tube, if patient intubated, to inhale over 15-30 sec; repeat qMin until IV sodium nitrite available

Each ampul lasts ~3 min; separate administration by at least 30 sec to allow patient to adequate oxygenate

Contraindications

Hypersensitivity to organic nitrates

Recent use (last 24 hr) sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra) or other phopsphodiesterase-5 inhibitor use

Caution in narrow angle glaucoma (controversial: may not be clinically significant)

Severe anemia

Recent head trauma

Cautions

AMI, alcohol use, hyperthyroidism, cardiomyopathy, incr ICP (eg, head, trauma, cerebral hemorrhage-potential contraindication), incr IOP, postural hypotension, volume depletion, low systolic BP

Inability to relieve chest pain after 3 doses may mean AMI-rush to ER if possible

Avoid excessive, prolonged hypotension

Withdraw gradually to avoid acute angina

Patient should be sitting down during & immediately after inhaling

Do not change brands unintentionally as not all are bioequivalent

Treat drug-induced headache with aspirin or acetaminophen

Provide nitrate-free interval (10-12 hr or overnight) to avoid development of tolerance

Protect from light"

[think before following links] https://reference.medscape.com/drug/amyl-nitrite-342274?icd=login_success_email_match_norm#10

[hntnhole]

I have utmost respect for folks who can (and do) offer this kind of in-depth information, let alone actual experience.  Just reading this makes me light-headed - literally. 

May Whatever bless and keep those who take care of the rest of us.  Merely a tiny cut on a finger or something makes me vomacious and light-headed.  

[GexTrick]

3 hours ago, hntnhole said:

I have utmost respect for folks who can (and do) offer this kind of in-depth information, let alone actual experience.

yea, couldnt agree more!
thanks a lot @tallslenderguy for the hyperqualified contibute

[KindaBasic]

6 hours ago, tallslenderguy said:

I also think there is a possible psychological effect.

There is something to that. I used to play quite a bit with a dom and I some of the most intense rushes whenever he “forced” me to inhale - especially blindfolded. I thought it was the brand he used, only to find out it was my own bottle he was using. The mind, especially pumped up on hormones and adrenaline, is a curious thing. 

[stillbreedin]

Posted Friday at 09:07 PM

As already stated, a break might help. The Leather Man in NYC has the legendary Brown Bottle that kicks my ass even when I’ve become desensitized to most brands. It used to be you could only by it in the store cash only. You can now get it Briarwalk.com.  It’s not the cheapest, but damn!

[stillbreedin]

thanks for the info on brown bottle and thanks to the guy who suggested storing poppers upside down.

[KindaBasic]

On 10/14/2024 at 6:32 PM, stillbreedin said:

thanks for the info on brown bottle and thanks to the guy who suggested storing poppers upside down.

Great stuff. I usually get a large bottle and divide it up into some smaller bottles I have kept. It is especially amazing stuff if I am in the mood for some hardcore goon time.