Hi Kazore,
Just saw your question.
The protocol for the Ipergay trial is:
2 Truvadas at least 2 hours before sex
Then 1 Truvada every 24 hours
For 48 hours after last sexual contact
So let's assume I'm going to have sex only on Friday night. I'll take 2 pills Friday morning, 1 Saturday morning, 1 Sunday morning, then stop.
If I'm going to have sex Friday night, Saturday, Monday night, and Tuesday night, I'll take 2 pills Friday morning, 1 every morning until Thursday.
So if you have sex pretty often, you take it every day. But if you stop having sex for a period of time, you stop the Truvada.
I'm in a relationship so I don't hook up a lot. At the beginning of the trial, I was single and very sexually active, 95% top, fucking probably 150 guys a year. I've never really bottomed and taken loads even on Truvada. I may start now that Truvada has been proven effective -- but until November, the Ipergay trial was double-blind with a placebo arm, so I couldn't be sure I was on Truvada or the placebo. They only gave everyone Truvada in November when they realized so many guys in the placebo arm were seroconverting.
I was comfortable with the risk of being a bareback top even if it was the placebo. And I'm rather uneasy about being a bareback bottom even on Truvada, because of the risk of hep C or HPV/warts/anal cancer.
So in the end I'll probably take Truvada with my boyfriend so that we can have some hot bareback orgies a few times a year.