Monkeypox

[CumAddict]

Just done it a few hours ago. Ten days later, the world will be more safe.

[ellentonboy]

 I just find it disappointing and upsetting that a Ryan White Case Manager, who has a client with monkeypox, can not tell me the location of the closest vaccine distribution center.  I know I have to advocate for my own health but it's a bit demoralizing to not get any assistance.

I see my infectious disease specialist on Tuesday, hopefully he or his staff will have some answers.  I watch the news and they mention the total number of cases, county by county, but no information on vaccines and where or how to get one.  

[hntnhole]

6 hours ago, ErosWired said:

phlebotomists from testing labs LabCorp and Quest are refusing to draw blood from suspected Monkeypox patients.

I saw that too on tv too .... since when do the employees at LC and Q get to decide which tests they'll handle and which they won't ???  

[fuckholedc]

R0 (the reproductive number, the average number of new cases that arise from a single currently infectious person) estimated to be 1.29.  Therefore it should be (somewhat easily) stoppable.  (Original COVID was about 3, measles is 16-18).

Quote

Monkeypox, a fast-spreading viral zoonosis outside of Africa in May 2022, has scientists on alert. We estimated the reproduction number to be 1.29 (95% CrI: 1.26, 1.33) by aggregating all cases in 70 countries as of July 22, 2022.

[think before following links] https://www.medrxiv.org/content/10.1101/2022.07.26.22278042v1 

[NEDenver]

8 hours ago, ErosWired said:

Aaaand in the news today, some phlebotomists from testing labs LabCorp and Quest are refusing to draw blood from suspected Monkeypox patients.

I mean, it’s not like they took a job to test for diseases or something…

[think before following links] [think before following links] https://www.cnn.com/2022/08/03/health/monkeypox-blood-phlebotomists/index.html

They’re supposed to wear gloves and a mask already.  The actual fuck, people.

[myDNA4u]

The biggest shame in the federal government's response to this is that in the Strategic National Stockpile there is over100 million does of the older ACAM2000 vaccine. This is like the smallpox vaccine I got first as a baby and then before going to college. While there can be some minor side effects and if it takes it will leave a small scar like the one on my left shoulder,  otherwise healthy people have very little to be concerned about. Releasing even a small percentage of this would end this issue and probably be more cost effective. Also it only requires a single dose.

Edited August 4, 2022 by myDNA4u
Missed a word

[tighthole64]

15 hours ago, hntnhole said:

I saw that too on tv too .... since when do the employees at LC and Q get to decide which tests they'll handle and which they won't ???  

Sadly it's similar to pharmacists, or clerks that refuse to sell birth control to individuals!  I know that doesn't effect anyone here, but saw a story where a Walgreens clerk refused to check out a woman trying to buy birth control.  Honestly forget if it was condoms, or pills, but shouldn't matter.  Woman had to get Mgr to complete transaction!

[ellentonboy]

Getting no help from  Governor DeSantis.  Yesterday's news showed him stating that NO state of emergency regarding monkeypox would be declared in Florida.   Currently Florida ranks 5th in cases, with the largest number in Broward county.  

His reasoning, he is trying to protect an individual's "personal liberties" and not force people to do something they don't want to do.  WTF?

What I took from that was just is utter lack of concern, "it's not our problem" attitude.  He should  tell that to the over 500 people in this state who have monkeypox.  God, I hope we can vote him out of office this fall.

[NWUSHorny]

2 hours ago, myDNA4u said:

The biggest shame in the federal government's response to this is that in the Strategic National Stockpile there is over100 million does of the older ACAM2000 vaccine. This is like the smallpox vaccine I got first as a baby and then before going to college. While there can be some minor side effects and if it takes it will leave a small scar like the one on my left shoulder,  otherwise healthy people have very little to be concerned about. Releasing even a small percentage of this would end this issue and probably be more cost effective. Also it only requires a single dose.

I've been thinking about this too. From what I've been able to find out, there are some additional risks with this vaccine. On the flip side I would be perfectly willing to explore the idea of taking it with my regular doctor before rejecting it completely.

[rawTOP]

1 hour ago, ellentonboy said:

Getting no help from  Governor DeSantis.  Yesterday's news showed him stating that NO state of emergency regarding monkeypox would be declared in Florida.   Currently Florida ranks 5th in cases, with the largest number in Broward county.  

His reasoning, he is trying to protect an individual's "personal liberties" and not force people to do something they don't want to do.  WTF?

What I took from that was just is utter lack of concern, "it's not our problem" attitude.  He should  tell that to the over 500 people in this state who have monkeypox.  God, I hope we can vote him out of office this fall.

I think his quote was "We don't live in fear" at which point I was thinking "yeah, but people in your state are going to be living in pain…" And his surgeon general was trying to boo hoo the vaccine saying it hasn't been tested enough on people.

This is why I live in a deep blue state. I honestly don't understand why anyone would want to live in a red state.

[ellentonboy]

I am wondering how governors in red states are going to react now that the White House has declared Monkeypox a national emergency.  Turn down funds perhaps?  Refuse to set up testing centers? I just heard it announced at the 1:00 pm news on MSNBC.  There weren't any details except I believe the head of HHS would be speaking sometime today.

As a Floridian, all I can do is sit and wait.

[bbm4matl]

1 hour ago, NWUSHorny said:

I've been thinking about this too. From what I've been able to find out, there are some additional risks with this vaccine. On the flip side I would be perfectly willing to explore the idea of taking it with my regular doctor before rejecting it completely.

I asked my primary care physician about this.  He said the smallpox vaccine has risks he considered significant, potentially life threatening if you’re unlucky. 

[myDNA4u]

2 hours ago, NWUSHorny said:

I've been thinking about this too. From what I've been able to find out, there are some additional risks with this vaccine. On the flip side I would be perfectly willing to explore the idea of taking it with my regular doctor before rejecting it completely.

Considering that this is like the smallpox vaccine I got as a child which was an absolute requirement to attend school (and there was no exemption for any reason including religion), I would not be concerned in the least. It was also required for anyone returning from overseas at the time. We have all let the anti-vaxers scare us into worrying about extremely rare and non- fatal reactions to vaccines. 

[topblkmale]

46 minutes ago, ellentonboy said:

I am wondering how governors in red states are going to react now that the White House has declared Monkeypox a national emergency.  

By shutting down all the gay bath houses.

[EuroMusk76]

4 hours ago, myDNA4u said:

The biggest shame in the federal government's response to this is that in the Strategic National Stockpile there is over100 million does of the older ACAM2000 vaccine. This is like the smallpox vaccine I got first as a baby and then before going to college. While there can be some minor side effects and if it takes it will leave a small scar like the one on my left shoulder,  otherwise healthy people have very little to be concerned about. Releasing even a small percentage of this would end this issue and probably be more cost effective. Also it only requires a single dose.

Unfortunately it's not quite as simple. Leaving aside the issue of side effects (which are major not just minor), there are at least three important reasons not to use ACAM2000 to combat Monkeypox. 

First of all it's quite difficult to vaccinate with ACAM2000.
Jynneos (called Imvanex in the EU/Imvamune in Canada) is given by subcutaneous injection. Every medical practitioner worth their salt should be able to do it.
ACAM2000  (and all older vaccines) is administered by scratching a bifurcated needle several times on the skin of the patient. It takes training, skill, and more time to administer than an injection. As a consequence only a small percentage of medical personnel will be qualified to do it. Let's have a look at a description of the procedure:

Quote

The bifurcated needle is a narrow steel rod, approximately 5 cm (2 in) long with two prongs at one end. It was designed to hold one dose of reconstituted freeze-dried smallpox vaccine between its prongs. Up to one hundred vaccinations can be given from one vial of the reconstituted vaccine.

The established technique for smallpox vaccination is to dip the needle in the vaccine, and then perpendicularly puncture a person's upper arm fifteen times rapidly in a small circular area, without prior cleansing of the skin with alcohol. The punctures should remain in an area approximately 5 mm in diameter. The needle is then disposed of. When done correctly a trace of blood appears at the vaccination site within 10 to 20 seconds after the procedure.

Source: [think before following links] https://en.m.wikipedia.org/wiki/Bifurcated_needle

A second major concern is fewer people can be vaccinated due to contraindications.
ACAM2000 can't be used in immunocompromised patients (HIV/AIDS or Chemotherapy) or patients with a history of eczema. That excludes some of the people most vulnerable to Monkeypox. Unfortunately it's not just healthy persons who need to be protected.
Jynneos is safer to use in patients with the preconditions mentioned above. Thus allowing to protect more people.

The third drawback of ACAM2000 is the danger of transmission to others by way of the vaccination lesion.
Older vaccines such as ACAM2000 use a live Vaccinia virus which is able to replicate. After vaccination one has a localized infection, with a red itchy sore. You may spread it inadvertently to others (by touch, shared objects and so on) if not enough care preventing contact with the lesion is taken. It's advisable to cover the lesion until the vaccination "takes" (i.e. essentially the Vaccinia infection has run its course). As it's in the hands of the patient to keep it covered it's certainly a procedure more prone to mistakes. One can understand that those responsible are a bit uneasy of that.
The Modified Virus Ankara (MVA) used in Jynneos can't replicate. Furthermore the mode of delivery doesn't create a lesion.

The slow response and the laggard pace of vaccination efforts makes me angry. Using older stockpiled smallpox vaccines doesn't appear to be the solution to me, however.